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Fluconazole increases the concentration of Celecoxib in the liver. Celecoxib should only be used in pregnant women when the benefits outweigh the potential risk to the fetus. Individuals who have developed allergic reactions from aspirin or other NSAIDs may experience an allergic reaction to Celecoxib and should not take Celecoxib. This medicine. Your doctor if you experience flatulence or diarrhea dizziness headache or insomnia. The breakdown of Celecoxib in the body called cyclo-oxygenase. The progression of either type of arthritis.